武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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TRIM56 Rabbit mAb

Anti-TRIM56 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263026

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263026
产品全名:   TRIM56 兔单克隆抗体
基因符号   RING finger protein 109; RNF109
UNIPROT ID:   Q9BRZ2
背景:   E3 ubiquitin-protein ligase that plays a key role in innate antiviral immunity (PubMed:21289118). In response to pathogen- and host-derived double-stranded DNA (dsDNA), targets TMEM173/STING to ‘Lys-63’-linked ubiquitination, thereby promoting its homodimerization, a step required for the production of type I interferon IFN-beta . Independently of its E3 ubiquitin ligase activity, positive regulator of TLR3 signaling. Potentiates extracellular double stranded RNA (dsRNA)-induced expression of IFNB1 and interferon-stimulated genes ISG15, IFIT1/ISG56, CXCL10, OASL and CCL5/RANTES. Promotes establishment of an antiviral state by TLR3 ligand and TLR3-mediated chemokine induction following infection by hepatitis C virus (PubMed:22948160).
抗原:   A synthetic peptide of human TRIM56
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R02-8A3
分子量:   Calculated MW: 81 kDa; Observed MW: 81 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of TRIM56(green) in Hela using TRIM56 antibody,and DAPI(blue)

Western blot analysis of TRIM56 in Hela lysates using TRIM56 antibody.
           引用文献