武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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TIAM2 Rabbit mAb

Anti-TIAM2 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262995

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262995
产品全名:   TIAM2 兔单克隆抗体
基因符号   STEF; TIAM-2
UNIPROT ID:   Q8IVF5
背景:   Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane . Activates specifically RAC1, but not CDC42 and RHOA.
抗原:   Recombinant protein of human TIAM2
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R09-8G7
分子量:   Calculated MW: 190 kDa; Observed MW: 190 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of TIAM2 in K562, 293 lysates using TIAM2 antibody.
           引用文献