| 货号: S210612 |
| 产品全名: SYT17 兔多抗 |
| 基因符号 sytXVII |
| UNIPROT ID: Q9BSW7 (Gene Accession – BC004518 ) |
| 背景: Synaptotagmin XVII (SytXVII), also known as Synaptotagmin-17 (SYT17) or Protein B/K, is a 474 amino acid peripheral membrane protein that belongs to the Synaptotagmin family and contains two C2 domains. While expressed abundantly in brain (frontal and temporal lobes, hippocampus, hypothalamus, amygdala, substantia nigra and pituitary), kidney and prostate, Synaptotagmin XVII is also expressed in fetal brain, kidney and lung. The gene that encodes Synaptotagmin XVII contains 100,082 bases and maps to human chromosome 16p12.3. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders, such as giant axonal neuropathy, Rubinstein-Taybi syndrome and Crohn’s disease. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
| 抗原: Fusion protein of human SYT17 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 50-200;WB: 200-1000;ELISA: 1000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 210612(SYT17 Antibody) at a dilution of 1/60(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 210612(Anti-SYT17 Antibody) at dilution 1/60. | 
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 210612(Anti-SYT17 Antibody) at a dilution of 1/60. | 
In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with fusion protein and then with D121278(Anti-SYT17 Antibody) at dilution 1/60. | 
Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse kidney tissue;
Primary antibody: 210612(SYT17 Antibody) at dilution 1/650;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute | |
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