| 货号: S219220 |
| 产品全名: STK32A 兔多抗 |
| 基因符号 YANK1 |
| UNIPROT ID: Q8WU08 (Gene Accession – BC021666 ) |
| 背景: The phosphorylation of proteins by protein kinases and protein phosphatases is a key event in most nuclear and cytoplasmic processes. The ability to activate and deactivate proteins via phosphorylation or dephosphorylation is important for cell division, cell differentiation, DNA repair and transcription. STK32A (serine/threonine kinase 32A), also known as YANK1, is a 396 amino acid protein that belongs to the superfamily of serine/threonine protein kinases and exists as three isoforms. The gene encoding STK32A maps to human chromosome 5, which is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| 抗原: Fusion protein of human STK32A |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 100-200;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219220(STK32A Antibody) at a dilution of 1/95(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219220(Anti-STK32A Antibody) at dilution 1/95. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse heart tissue lysate;
Primary antibody: 219220(STK32A Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds | |
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