武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

STK3 Rabbit mAb

Anti-STK3 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262946

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262946
产品全名:   STK3 兔单克隆抗体
基因符号   STK3; Mess1; MST-2; MST2; Serine/threonine kinase 3; KRS1; STE20-like kinase MST2
UNIPROT ID:   Q13188
背景:   Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
抗原:   A synthetic peptide of human STK3
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R04-8D3
分子量:   Calculated MW: 56 kDa; Observed MW: 56 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat,Hamster
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using STK3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of STK3/MST2 in 3T3, Raw264.7 lysates using STK3 antibody.

Western blot analysis of STK3/MST2 in CHO-K1, C6, Jurkat lysates using STK3/MST2 antibody.
           引用文献