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SLC12A3 Rabbit pAb

Anti-SLC12A3 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221404

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221404
产品全名:   SLC12A3 兔多抗
基因符号   NCC; TSC; NCCT
UNIPROT ID:   P55017 (Gene Accession – NP_001119580 )
背景:   This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter’s syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
抗原:   Synthetic peptide of human SLC12A3
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: Oct-50; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 221404(SLC12A3 Antibody) at a dilution of 1/25(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 221404(Anti-SLC12A3 Antibody) at dilution 1/25.
           引用文献