武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RUNX1T1 Rabbit pAb

Anti-RUNX1T1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S220867

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S220867
产品全名:   RUNX1T1 兔多抗
基因符号   CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1
UNIPROT ID:   Q06455 (Gene Accession – NP_001185554 )
背景:   This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5′-region of the runt-related transcription factor 1 gene fused to the 3′-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
抗原:   Synthetic peptide of human RUNX1T1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 220867(RUNX1T1 Antibody) at a dilution of 1/35(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 220867(Anti-RUNX1T1 Antibody) at dilution 1/35.
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