武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RASSF1 Rabbit pAb

Anti-RASSF1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S211477

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S211477
产品全名:   RASSF1 兔多抗
基因符号   123F2; RDA32; NORE2A; RASSF1A; REH3P21
UNIPROT ID:   Q9NS23 (Gene Accession – BC110412 )
背景:   This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
抗原:   Fusion protein of human RASSF1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 211477(RASSF1 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 211477(Anti-RASSF1 Antibody) at dilution 1/20.
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