武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RASA4 Rabbit pAb

Anti-RASA4 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217738

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217738
产品全名:   RASA4 兔多抗
基因符号   GAPL; CAPRI
UNIPROT ID:   O43374 (Gene Accession – BC113663 )
背景:   This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [
抗原:   Fusion protein of human RASA4
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: Oct-50; ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217738(RASA4 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217738(Anti-RASA4 Antibody) at dilution 1/20.
           引用文献