武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Rad51D Rabbit mAb

Anti-Rad51D Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262804

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262804
产品全名:   Rad51D 兔单克隆抗体
基因符号   TRAD; R51H3; BROVCA4; RAD51L3
UNIPROT ID:   O75771
背景:   Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.
抗原:   Recombinant protein of human Rad51D
经过测试的应用:   WB,IP
推荐稀释比:   WB: 1/500-1/1000 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R03-9E6
分子量:   Calculated MW: 35 kDa; Observed MW: 35 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Rad51D in K562, C6, 3T3, Hela lysates using Rad51D antibody.
           引用文献