武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RAD50 Rabbit pAb

Anti-RAD50 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S213727

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S213727
产品全名:   RAD50 兔多抗
基因符号   NBSLD; RAD502; hRad50
UNIPROT ID:   Q92878 (Gene Accession – NP_005723 )
背景:   The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
抗原:   Synthetic peptide of human RAD50
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-100;WB: 500-2000;ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using 213727(RAD50 Antibody) at a dilution of 1/40(Nucleus).

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: 293T, Hela, K562, NIH/3T3, RAW264.7 cell lysates;
Primary antibody: 213727(RAD50 Antibody) at dilution 1/900;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 minutes
           引用文献