武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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RAD23B Rabbit pAb

Anti-RAD23B Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218689

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218689
产品全名:   RAD23B 兔多抗
基因符号   P58; HR23B; HHR23B
UNIPROT ID:   P54727 (Gene Accession – BC020973 )
背景:   The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
抗原:   Fusion protein of human RAD23B
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 218689(RAD23B Antibody) at a dilution of 1/30(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 218689(Anti-RAD23B Antibody) at dilution 1/30.
           引用文献