武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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PPM1M Rabbit pAb

Anti-PPM1M Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219284

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219284
产品全名:   PPM1M 兔多抗
基因符号   PP2CE; PP2Ceta; PP2C-eta
UNIPROT ID:   Q96MI6 (Gene Accession – BC009644 )
背景:   PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
抗原:   Fusion protein of human PPM1M
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 100-300; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219284(PPM1M Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219284(Anti-PPM1M Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219284(Anti-PPM1M Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D226205(Anti-PPM1M Antibody) at dilution 1/100.
           引用文献