武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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PMS2 Rabbit pAb

Anti-PMS2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225564

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225564
产品全名:   PMS2 兔多抗
基因符号   DNA mismatch repair gene; DNA mismatch repair protein PMS2; HNPCC4; PMS1 protein homolog 2
UNIPROT ID:   P54278
背景:   Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected.
抗原:   A synthesized peptide derived from human PMS2
经过测试的应用:   WB,IHC-P,ICC/IF,IP,FC
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 96 kDa; Observed MW: 110 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using PMS2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of PMS2 in (1) Jurkat lysates; (2)HeLa lysates using PMS2 antibody.
           引用文献