武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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PLOD2 Rabbit pAb

Anti-PLOD2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218914

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218914
产品全名:   PLOD2 兔多抗
基因符号   LH2; TLH; BRKS2
UNIPROT ID:   O00469 (Gene Accession – BC037169 )
背景:   The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
抗原:   Fusion protein of human PLOD2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 150-300; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cancer, Cardiovascular, Metabolism
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218914(PLOD2 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218914(Anti-PLOD2 Antibody) at dilution 1/100.
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