| 货号: N261375 |
| 产品全名: PI3 Kinase p85 alpha (1C8) 小鼠单抗 |
| 基因符号 PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha |
| UNIPROT ID: P27986 |
| 背景: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
| 抗原: Purified recombinant protein expressed in E.coli. |
| 经过测试的应用: WB,IHC-P |
| 推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 |
| 种属反应性: Mouse |
| 克隆性： Mouse Monoclonal |
| 克隆编号: 1C8-2H4-9D9 |
| 分子量: Calculated MW: 84 kDa; Observed MW: 84 kDa |
| 亚型: IgG1 |
| 纯化: Affinity Purified |
| 种属反应性: Human, Mouse and Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemical analysis of paraffin-embedded Human tonsils using PI3 Kinase p85 alpha (1C8) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. | 
Immunohistochemistry analysis of paraffin-embedded rat Liver Tissue using PI3 Kinase p85 alpha (1C8) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. | 
Western blot analysis of PI3 Kinase p85 alpha (1C8) in Jurkat, rat Brain, Raw264.7, Ramos, Raji lysates using PI3 Kinase p85 alpha (1C8) antibody | 
Western blot analysis of PI3 Kinase p85 alpha (1C8) in Hela, A549, HL-60, U2OS, C6 lysates using PI3 Kinase p85 alpha (1C8) antibody. |
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