武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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NEDD4L Rabbit pAb

Anti-NEDD4L Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217646

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217646
产品全名:   NEDD4L 兔多抗
基因符号   RSP5; NEDD4-2; NEDD4.2; hNEDD4-2
UNIPROT ID:   Q96PU5 (Gene Accession – BC032597 )
背景:   This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
抗原:   Fusion protein of human NEDD4L
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 217646(NEDD4L Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 217646(Anti-NEDD4L Antibody) at dilution 1/50.
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