武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MSH6 Rabbit pAb

Anti-MSH6 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216656

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216656
产品全名:   MSH6 兔多抗
基因符号   GTBP; HSAP; p160; GTMBP; HNPCC5
UNIPROT ID:   P52701 (Gene Accession – BC004246 )
背景:   This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
抗原:   Fusion protein of human MSH6
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human cervical cancer tissue using 216656(MSH6 Antibody) at a dilution of 1/120(Nucleus).

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: LOVO cell lysate;
Primary antibody: 216656(MSH6 Antibody) at dilution 1/900;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 minutes
           引用文献