武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MSH2 Rabbit pAb

Anti-MSH2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221854

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221854
产品全名:   MSH2 兔多抗
基因符号   FCC1; COCA1; HNPCC; LCFS2; HNPCC1
UNIPROT ID:   P43246 (Gene Accession – NP_000242 )
背景:   This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
抗原:   Synthetic peptide of human MSH2
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 20-100;WB: 200-1000;ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221854(MSH2 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221854(Anti-MSH2 Antibody) at dilution 1/20.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: HEPG2, 293T, SKOV3, Hela and A172 cell lysates;
Primary antibody: 221854(MSH2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
           引用文献