| 货号: S217610 |
| 产品全名: MRE11 兔多抗 |
| 基因符号 ATLD; HNGS1; MRE11A; MRE11B |
| UNIPROT ID: P49959 (Gene Accession – NP_005582 ) |
| 背景: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3′ to 5′ exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3′ to 5′ exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
| 抗原: Fusion protein of human MRE11 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 100-300; ELISA: 2000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217610(MRE11 Antibody) at a dilution of 1/60(Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217610(Anti-MRE11 Antibody) at dilution 1/60. | 
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 217610(Anti-MRE11 Antibody) at a dilution of 1/60. | 
In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D222698(Anti-MRE11 Antibody) at dilution 1/60. |
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