武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MRE11 Rabbit pAb

Anti-MRE11 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S214495

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S214495
产品全名:   MRE11 兔多抗
基因符号   ATLD; HNGS1; MRE11A; MRE11B
UNIPROT ID:   P49959 (Gene Accession – NP_005582 )
背景:   This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3′ to 5′ exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3′ to 5′ exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
抗原:   Synthetic peptide of human MRE11
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 214495(MRE11 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 214495(Anti-MRE11 Antibody) at dilution 1/20.
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