武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MDC1 Rabbit pAb

Anti-MDC1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S213896

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S213896
产品全名:   MDC1 兔多抗
基因符号   NFBD1
UNIPROT ID:   Q14676 (Gene Accession – NP_055456 )
背景:   The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
抗原:   Synthetic peptide of human MDC1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 100-300; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 213896(MDC1 Antibody) at a dilution of 1/80(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 213896(Anti-MDC1 Antibody) at dilution 1/80.
           引用文献