武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MCM10 Rabbit pAb

Anti-MCM10 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216637

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216637
产品全名:   MCM10 兔多抗
基因符号   CNA43; DNA43; PRO2249
UNIPROT ID:   Q7L590 (Gene Accession – BC009108 )
背景:   The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
抗原:   Fusion protein of human MCM10
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human brain tissue using 216637(MCM10 Antibody) at a dilution of 1/45(Cytoplasm and Nucleus).
           引用文献