武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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MAPKAPK5 Rabbit pAb

Anti-MAPKAPK5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217592

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217592
产品全名:   MAPKAPK5 兔多抗
基因符号   MK5; MK-5; PRAK; MAPKAP-K5
UNIPROT ID:   Q8IW41 (Gene Accession – BC041049 )
背景:   The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
抗原:   Fusion protein of human MAPKAPK5
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 217592(MAPKAPK5 Antibody) at a dilution of 1/35(Nucleus and Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 217592(Anti-MAPKAPK5 Antibody) at dilution 1/35.
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