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Ku70 (7B1) Mouse mAb

Anti-Ku70 (7B1) Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261121

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261121
产品全名:   Ku70 (7B1) 小鼠单抗
基因符号   XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5′-deoxyribose-5-phosphate lyase Ku70; 5′-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
UNIPROT ID:   P12956
背景:   It works in the 3′-5′ direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
抗原:   Purified recombinant human Ku70 protein fragments expressed in E.coli.
经过测试的应用:   WB,ICC/IF,IP,ChIP
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   7B1-E12-G4
分子量:   Calculated MW: 70 kDa; Observed MW: 67 kDa
亚型:   IgG1
纯化:   Affinity Purified
种属反应性:   Human,Monkey
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Ku70 (7B1) in HeLa using Ku70 antibody.

Western blot analysis of Ku70 in Hela, A549, COS7 and K562 lysates using Ku70 antibody.

Immunoprecipitation analysis of Ku70 (7B1) in Hela lysates using Ku7 antibody.
           引用文献