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Ku70 (6H10) Mouse mAb

Anti-Ku70 (6H10) Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261438

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261438
产品全名:   Ku70 (6H10) 小鼠单抗
基因符号   XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5′-deoxyribose-5-phosphate lyase Ku70; 5′-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
UNIPROT ID:   P12956
背景:   It works in the 3′-5′ direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
抗原:   Purified recombinant human Ku70 protein fragments expressed in E.coli.
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   6H10-E9-G7
分子量:   Calculated MW: 70 kDa; Observed MW: 70 kDa
亚型:   IgG2b
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing
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