武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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IL6ST Rabbit pAb

Anti-IL6ST Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S214897

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S214897
产品全名:   IL6ST 兔多抗
基因符号   CD130; GP130; CDW130; IL-6RB
UNIPROT ID:   P40189 (Gene Accession – NP_002175 )
背景:   The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
抗原:   Synthetic peptide of human IL6ST
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cancer, Cardiovascular, Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 214897(IL6ST Antibody) at a dilution of 1/30(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 214897(Anti-IL6ST Antibody) at dilution 1/30.
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