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IL-10 Receptor alpha Rabbit pAb

Anti-IL-10 Receptor alpha Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225196

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225196
产品全名:   IL-10 Receptor alpha 兔多抗
基因符号   IL10RA; IL10R; Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD antigen CD210
UNIPROT ID:   Q13651
背景:   The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
抗原:   The antiserum was produced against synthesized peptide derived from the Internal region of human IL10RA. AA range:151-200
经过测试的应用:   WB,ELISA
推荐稀释比:   WB: 1/500-1/1000 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 63 kDa; Observed MW: 63 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of IL-10 Receptor alpha in PC-12 lysates using IL-10 Receptor alpha antibody.
           引用文献