武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

HMG4 Rabbit mAb

Anti-HMG4 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263369

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263369
产品全名:   HMG4 兔单克隆抗体
基因符号   HMG4; HMG-4; HMG2A; HMG-2a
UNIPROT ID:   O15347
背景:   Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters . Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor . Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling .
抗原:   A synthetic peptide of human HMG4
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R08-1C7
分子量:   Calculated MW: 23 kDa; Observed MW: 23 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using HMG4 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of HMG4 in 3T3 lysates using HMG4 antibody.

Western blot analysis of HMG4 in Hela, A549, HL-60, U2OS, C6 lysates using HMG4 antibody.
           引用文献