武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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HDAC5 Rabbit pAb

Anti-HDAC5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225447

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225447
产品全名:   HDAC5 兔多抗
基因符号   HD5; NY-CO-9
UNIPROT ID:   Q9UQL6
背景:   Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
抗原:   The antiserum was produced against synthesized peptide derived from human HDAC5. AA range:464-513
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF,ELISA
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 122 kDa; Observed MW: 122 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human,Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using HDAC5 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of HDAC5 in various lysates using HDAC5 antibody.

Western blot analysis of HDAC5 in K562 lysates using HDAC5 antibody.

Western blot analysis of HDAC5 in colo lysates using HDAC5 antibody.The lane on the right is blocked with the synthesized peptide.
           引用文献