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Glucocorticoid Receptor Rabbit mAb

Anti-Glucocorticoid Receptor Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262278

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262278
产品全名:   Glucocorticoid Receptor 兔单克隆抗体
基因符号   GR; GCR; GRL; GCCR; GCRST
UNIPROT ID:   P06537
背景:   Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5′ UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay . Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth.
抗原:   Recombinant protein of mouse Glucocorticoid Receptor
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R04-8C8
分子量:   Calculated MW: 87 kDa; Observed MW: 94,91 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Glucocorticoid Receptor(green) in Hela using Glucocorticoid Receptor antibody,and DAPI(blue)

Western blot analysis of Glucocorticoid Receptor in rat skeletal muscle lysates using Glucocorticoid Receptor antibody.

Western blot analysis of Glucocorticoid Receptor in K562, 3T3, Hela lysates using Glucocorticoid Receptor antibody.
           引用文献