武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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GABARAPL2 Rabbit pAb

Anti-GABARAPL2 Rabbit Polyclonal Antibody
5/5

$2,850.00

货号:S219188

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219188
产品全名:   GABARAPL2 兔多抗
基因符号   ATG8; GEF2; ATG8C; GEF-2; GATE16; GATE-16
UNIPROT ID:   P60520 (Gene Accession – BC029601 )
背景:   Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
抗原:   Fusion protein of human GABARAPL2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 40-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cell Biology, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 219188(GABARAPL2 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 219188(Anti-GABARAPL2 Antibody) at dilution 1/55.
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