| 货号: S222023 |
| 产品全名: FBXW8 兔多抗 |
| 基因符号 FBW6; FBW8; FBX29; FBXW6; FBXO29 |
| UNIPROT ID: Q8N3Y1 (Gene Accession – NP_699179 ) |
| 背景: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
| 抗原: Synthetic peptide of human FBXW8 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 40-200; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 222023(FBXW8 Antibody) at a dilution of 1/70(Cytoplasm or Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 222023(Anti-FBXW8 Antibody) at dilution 1/70. | 
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 222023(Anti-FBXW8 Antibody) at a dilution of 1/70. | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D263900(Anti-FBXW8 Antibody) at dilution 1/70. |
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