武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Factor VIII Rabbit pAb

Anti-Factor VIII Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225444

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225444
产品全名:   Factor VIII 兔多抗
基因符号   F8; F8C; Coagulation factor VIII; Antihemophilic factor; AHF; Procoagulant component
UNIPROT ID:   P00451
背景:   F8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
抗原:   Synthesized peptide derived from the C-terminal region of human Factor VIII. at AA rangle: 2130-2210
经过测试的应用:   WB,IHC-P,ELISA
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 267 kDa; Observed MW: 300 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human,Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Factor VIII in HuvEc lysates using Factor VIII antibody.

Western blot analysis of Factor VIII in HuvEc lysates using Factor VIII antibody.
           引用文献