武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DROSHA Rabbit pAb

Anti-DROSHA Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S215687

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S215687
产品全名:   DROSHA 兔多抗
基因符号   RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976
UNIPROT ID:   Q9NRR4 (Gene Accession – NP_037367 )
背景:   This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein comple,x which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
抗原:   Synthetic peptide of human DROSHA
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 215687(DROSHA Antibody) at a dilution of 1/45(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 215687(Anti-DROSHA Antibody) at dilution 1/45.
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