武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DKK1 Rabbit pAb

Anti-DKK1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S210277

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S210277
产品全名:   DKK1 兔多抗
基因符号   SK; DKK-1
UNIPROT ID:   O94907 (Gene Accession – BC001539 )
背景:   This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines.
抗原:   Fusion protein of human DKK1
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-300;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cardiovascular, Immunology, Signal Transduction, Developmental Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 210277(DKK1 Antibody) at a dilution of 1/50(Secreted).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 210277(Anti-DKK1 Antibody) at dilution 1/50.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: PC-3 cell lysate;
Primary antibody: 210277(DKK1 Antibody) at dilution 1/600;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 40 seconds
           引用文献