武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DFFB Rabbit pAb

Anti-DFFB Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S213407

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S213407
产品全名:   DFFB 兔多抗
基因符号   CAD; CPAN; DFF2; DFF40; DFF-40
UNIPROT ID:   O76075 (Gene Accession – NP_004393.1 )
背景:   Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of these variants has not been determined.
抗原:   Synthetic peptide of human DFFB
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 1000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 213407(DFFB Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 213407(Anti-DFFB Antibody) at dilution 1/30.
           引用文献