武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CYFIP1 Rabbit pAb

Anti-CYFIP1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218561

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218561
产品全名:   CYFIP1 兔多抗
基因符号   SHYC; SRA1; SRA-1; P140SRA-1
UNIPROT ID:   Q7L576 (Gene Accession – BC005097 )
背景:   Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
抗原:   Fusion protein of human CYFIP1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-100; ELISA: 500-1000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218561(CYFIP1 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218561(Anti-CYFIP1 Antibody) at dilution 1/30.
           引用文献