武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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COX10 Rabbit pAb

Anti-COX10 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S216275

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S216275
产品全名:   COX10 兔多抗
基因符号   
UNIPROT ID:   Q12887 (Gene Accession – BC000060 )
背景:   Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.
抗原:   Fusion protein of human COX10
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 500-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human renal cancer tissue using 216275(COX10 Antibody) at a dilution of 1/100(Cytoplasm).
           引用文献