武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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Cofilin Rabbit pAb

Anti-Cofilin Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225279

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225279
产品全名:   Cofilin 兔多抗
基因符号   CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform
UNIPROT ID:   P23528
背景:   The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
抗原:   Peptide sequence around aa. 86~90 (A-T-Y-E-T) derived from Human coflin1/cofilin2.
经过测试的应用:   WB,IHC-P,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 19 kDa; Observed MW: 19 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunofluorescence analysis of Cofilin in Hela using coflin1/cofilin2 (Ab88) antibody.

Western blot analysis of Cofilin in MDA lysates using coflin1/cofilin2 (Ab88) antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using coflin1/cofilin2 (Ab88) antibody (left) or the same antibody preincubated with blocking peptide (right).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
           引用文献