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Cleaved-Caspase 4/5 p20 Rabbit pAb

Anti-Cleaved-Caspase 4/5 p20 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225494

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225494
产品全名:   Cleaved-Caspase 4/5 p20 兔多抗
基因符号   TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
UNIPROT ID:   P49662/P51878
背景:   CASP4 (caspase 4) encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, caspase 4 induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
抗原:   The antiserum was produced against synthesized peptide derived from human Caspase 4/5. AA range:221-270
经过测试的应用:   WB,ELISA
推荐稀释比:   WB: 1/500-1/1000 ELISA: 1/10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 43 kDa; Observed MW: 47,22 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human
Modification:   Cleaved
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   apoptosis – Caspase family
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Cleaved-Caspase 4/5 p20 in Jurkat lysates using Caspase 4/5 (p20, Cleaved-Asp270/Asp311) antibody. The lane on the right is blocked with the Caspase 4/5 (p20, Cleaved-Asp270/Asp311) peptide.
           引用文献