武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CLDN18 Rabbit pAb

Anti-CLDN18 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219710

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219710
产品全名:   CLDN18 兔多抗
基因符号   SFTA5; SFTPJ
UNIPROT ID:   P56856 (Gene Accession – NP_001002026 )
背景:   This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
抗原:   Synthetic peptide of human CLDN18
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 20-100; ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 219710(CLDN18 Antibody) at a dilution of 1/25(Cell membrane and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 219710(Anti-CLDN18 Antibody) at dilution 1/25.
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