| 货号: S218480 |
| 产品全名: CGREF1 兔多抗 |
| 基因符号 CGR11 |
| UNIPROT ID: Q99674 (Gene Accession – BC034764 ) |
| 背景: CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a gene located on human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr?m syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2. |
| 抗原: Fusion protein of human CGREF1 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 25-100; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218480(CGREF1 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218480(Anti-CGREF1 Antibody) at dilution 1/20. | 
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 218480(Anti-CGREF1 Antibody) at a dilution of 1/20. | 
In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D224529(Anti-CGREF1 Antibody) at dilution 1/20. |
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