武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CEMIP Rabbit pAb

Anti-CEMIP Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S222302

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S222302
产品全名:   CEMIP 兔多抗
基因符号   CCSP1; HYBID; TMEM2L; KIAA1199
UNIPROT ID:   Q8WUJ3 (Gene Accession – NP_061159 )
背景:   Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.
抗原:   Synthetic peptide of human CEMIP
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 222302(CEMIP Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 222302(Anti-CEMIP Antibody) at dilution 1/60.
           引用文献