武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CDC42BPA Rabbit pAb

Anti-CDC42BPA Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221705

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221705
产品全名:   CDC42BPA 兔多抗
基因符号   MRCK; MRCKA; PK428
UNIPROT ID:   Q5VT25 (Gene Accession – XP_005273381 )
背景:   The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.
抗原:   Synthetic peptide of human CDC42BPA
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 30-150;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221705(CDC42BPA Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221705(Anti-CDC42BPA Antibody) at dilution 1/45.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: A172 cell lysate;
Primary antibody: 221705(CDC42BPA Antibody) at dilution 1/600;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 minutes
           引用文献