武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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BLNK Rabbit mAb

Anti-BLNK Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N261927

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261927
产品全名:   BLNK 兔单克隆抗体
基因符号   BLNK; BASH; SLP65; B-cell linker protein; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; Cytoplasmic adapter protein; Src homology 2 domain-containing leukocyte protein of 65 kDa
UNIPROT ID:   Q8WV28
背景:   This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
抗原:   A synthetic peptide of human BLNK
经过测试的应用:   WB,IP
推荐稀释比:   WB: 1/500-1/1000 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R04-7H1
分子量:   Calculated MW: 50 kDa; Observed MW: 70 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of BLNK in K562, C6, 3T3, Hela lysates using BLNK antibody.
           引用文献