武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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BAP1 Rabbit pAb

Anti-BAP1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217150

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217150
产品全名:   BAP1 兔多抗
基因符号   UCHL2; hucep-6; HUCEP-13
UNIPROT ID:   Q92560 (Gene Accession – BC001596 )
背景:   This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
抗原:   Fusion protein of human BAP1
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer tissue using 217150(BAP1 Antibody) at a dilution of 1/70(Nucleus and Cytoplasm).

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: A549, PC-3, Jurkat cell lysates;
Primary antibody: 217150(BAP1 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
           引用文献