武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

微信:Neweast Biosciences

咨询:027 – 63497286 

Bak Rabbit mAb

Anti-Bak Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N261910

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261910
产品全名:   Bak 兔单克隆抗体
基因符号   BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7
UNIPROT ID:   Q16611
背景:   Bak is a proapoptotic member of the Bcl-2 family. This protein is located on the outer membrane of mitochondria and is an essential component for transduction of apoptotic signals through the mitochondrial pathway. Upon apoptotic stimulation, an upstream stimulator like truncated BID (tBID) induces conformational changes in Bak to form oligomer channels in the mitochondrial membrane for cytochrome c release. The release of cytochrome c to the cytosol activates the caspase-9 pathway and eventually leads to cell death.
抗原:   A synthetic peptide of human Bak
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R03-6A8
分子量:   Calculated MW: 23 kDa; Observed MW: 23 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   apoptosis – Bcl-2 family
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Bak antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Bak in K562, Hela lysates using Bak antibody.
           引用文献