武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N225874 |
产品全名: ATG7 兔多抗 |
基因符号 hAGP7; Ubiquitin-activating enzyme E1-like protein; APG7L |
UNIPROT ID: O95352 |
背景: The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10. |
抗原: A synthesized peptide derived from human Atg7(Apg7) |
经过测试的应用: WB,ICC/IF |
推荐稀释比: WB: 1/500-1/1000 IF: 1/50-1/200 |
种属反应性: Rabbit |
克隆性: Rabbit Polyclonal |
分子量: Calculated MW: 78 kDa; Observed MW: 78 kDa |
亚型: IgG |
纯化: Affinity Chromatography |
种属反应性: Human, Mouse and Rat |
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
研究领域: Autophag&yAutophagosome |
储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
![]() Western blot analysis of Atg7(Apg7) in (1) HepG2 lysates; (2) mouse spleen lysates; (3) rat kidney lysates using ATG7 antibody. |