武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ARIH1 Rabbit pAb

Anti-ARIH1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S215541

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S215541
产品全名:   ARIH1 兔多抗
基因符号   ARI; HARI; HHARI; UBCH7BP
UNIPROT ID:   Q9Y4X5 (Gene Accession – NP_005735 )
背景:   ARIH1 (ariadne homolog), also known as ubiquitin conjugating enzyme E2 binding protein 1, ARI, HARI, HHARI (human homolog of Drosophila ariadne), MOP-6 (monocyte protein 6) or UBCH7BP (UBCH7 binding protein), is a 557 amino acid cytoplasmic protein. Expressed in a wide variety of tissues, ARIH1 contains two RING-type zinc fingers and one IBR (in-between RING fingers)-type domain. ARIH1 is believed to be involved in protein degradation and protein translation. ARIH1 interacts with UBCH7 and is thought to function as an E3 ubiquitin-protein ligase (or as a component of an E3 complex) that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme (UBCH7) and transfers that ubiquitin residue to substrates targeted for degradation. Specifically, ARIH1 interacts with and polyubiquitylates eIF4E2, thereby targeting it for proteasomal degradation.
抗原:   Synthetic peptide of human ARIH1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 215541(ARIH1 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 215541(Anti-ARIH1 Antibody) at dilution 1/30.
           引用文献